Both are extracted from salmon testis DNA, with high homology and similar safety, butThe molecular structure, core effects, maintenance cycle, and skin adaptation are completely different, PN is an upgraded version of macromolecules, and PDRN is a small-molecule first-aid repair model.
1. Essential differences in molecular structures
- PDRN (polydeoxyribonucleotides)
- Short-chain small molecules, molecular weight 300 - 500 Daltons, single helix short segments, thin texture, strong mobility, fast penetration, only anti-inflammatory repair signals, no three-dimensional supporting structure.
- PN (polynucleotide)
- Long-chain macromolecule with a molecular weight of over 1000 Daltons, three-dimensional double helix scaffold, sticky and highly elastic; after entering the dermis, it will slowly decompose and continuously release PDRN, which has the dual functions of stent filling and long-term repair.
2. Focus on core efficacy
PDRN's main features: rapid anti-inflammation, first aid repair
- Effectively fade red, soothe sensitive periods, and repair post-medical barrier;
- Improve redness, acne muscle inflammation, laser/brushing acid damage to muscles, and repeated allergies;
- Mild collagen promotion, mainly to maintain stability, reduce redness, and brighten red acne marks;
- Quick results: You can feel that the skin is not hot or red, moist and stable 3 - 5 days after surgery.
PN's main features: deep anti-aging, reconstruction of dermis, long-term stability maintenance
- The three-dimensional scaffold supports the dermis layer and stimulates fibroblasts to produce a large amount of collagen and elastic fibers;
- Improve fine lines, thick pores, skin thinning, slack dryness, dark yellow air;
- Slowly release PDRN, anti-aging and long-term anti-inflammation, taking into account repair;
- Improve dry lines around the eyes, dark tear grooves, and light-aging skin at maturity, and improve skin smoothness more significantly.
3. Maintenance cycle and treatment frequency
- PDRN: Metabolism is fast, and the single effect lasts for about 1 month; it is suitable for high-frequency daily maintenance, once a month. Sensitive first aid can be used for intensive repair twice in a row.
- PN: Macromolecules remain for a long time and can be maintained for 2 - 3 months at a single time; regular courses of treatment are 3 times with an interval of 21 - 30 days. Long-term anti-aging is more cost-effective.
4. How to choose the appropriate group
PDRN is more appropriate
- Sensitive muscles, rosacea, perennial redness and burning;
- I just finished laser, dot matrix, and acid brushing, and needed first aid after surgery;
- There are many oily acne muscles and inflammatory acne marks, which will fade red after maintaining stability in the short term;
- Young and healthy skin, basic hydration maintains stability, and affordable daily water.
- Representative products: Dishu, platinum salmon basic style.
PN is more appropriate
- 28 + Thinning mature muscles and dermis, loose fine lines, and thick pores;
- The skin color is dark, dry and dull, and the face is ruined by staying up late;
- Fine lines around the eyes, dark circles, and dark tear grooves;
- I want to repair and anti-aging in one to reduce frequent projects.
- Representative products: Lizhu Blue Black Box, Libona PN.
5. Simply summarize one sentence
Choose PDRN for acute sensitivity, postoperative repair, and rapid fading of redness; choose PN for anti-aging, firming and delicate, and long-term skin nourishing.
It is often used together in clinical practice: PDRN is used to repair the inflammatory substrate first, and then PN is used to deeply rebuild collagen, taking into account first aid and long-term rejuvenation.
